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Synthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes

Synthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7a84110a601e4dbd8122cc98fa621c4d

Synthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes

About this item

Full title

Synthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-01, Vol.11 (1), p.598-14, Article 598

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The synthesis of a new series of Gd(III)-arylphosphonium complexes is described and the solution stability of selected compounds is reported. Their lipophilicity and uptake in human glial (SVG p12) and human glioblastoma multiforme (T98G) cell lines are presented. The in vitro cytotoxicity of all complexes was determined to be low at therapeuticall...

Alternative Titles

Full title

Synthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7a84110a601e4dbd8122cc98fa621c4d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7a84110a601e4dbd8122cc98fa621c4d

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-79893-9

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