Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export
Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export
About this item
Full title
Author / Creator
Heybrock, Saskia , Kanerva, Kristiina , Meng, Ying , Ing, Chris , Liang, Anna , Xiong, Zi-Jian , Weng, Xialian , Ah Kim, Young , Collins, Richard , Trimble, William , Pomès, Régis , Privé, Gilbert G. , Annaert, Wim , Schwake, Michael , Heeren, Joerg , Lüllmann-Rauch, Renate , Grinstein, Sergio , Ikonen, Elina , Saftig, Paul and Neculai, Dante
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The intracellular transport of cholesterol is subject to tight regulation. The structure of the lysosomal integral membrane protein type 2 (LIMP-2, also known as SCARB2) reveals a large cavity that traverses the molecule and resembles the cavity in SR-B1 that mediates lipid transfer. The detection of cholesterol within the LIMP-2 structure and the...
Alternative Titles
Full title
Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export
Authors, Artists and Contributors
Author / Creator
Kanerva, Kristiina
Meng, Ying
Ing, Chris
Liang, Anna
Xiong, Zi-Jian
Weng, Xialian
Ah Kim, Young
Collins, Richard
Trimble, William
Pomès, Régis
Privé, Gilbert G.
Annaert, Wim
Schwake, Michael
Heeren, Joerg
Lüllmann-Rauch, Renate
Grinstein, Sergio
Ikonen, Elina
Saftig, Paul
Neculai, Dante
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7ad18a0cfcb742e09b108e2916ba4cfd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7ad18a0cfcb742e09b108e2916ba4cfd
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11425-0
