Calcium handling precedes cardiac differentiation to initiate the first heartbeat
Calcium handling precedes cardiac differentiation to initiate the first heartbeat
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England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
The mammalian heartbeat is thought to begin just prior to the linear heart tube stage of development. How the initial contractions are established and the downstream consequences of the earliest contractile function on cardiac differentiation and morphogenesis have not been described. Using high-resolution live imaging of mouse embryos, we observed...
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Calcium handling precedes cardiac differentiation to initiate the first heartbeat
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TN_cdi_doaj_primary_oai_doaj_org_article_7b0318b9436e4a8fb4d03847c3efd7d4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b0318b9436e4a8fb4d03847c3efd7d4
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.17113