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Calcium handling precedes cardiac differentiation to initiate the first heartbeat

Calcium handling precedes cardiac differentiation to initiate the first heartbeat

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b0318b9436e4a8fb4d03847c3efd7d4

Calcium handling precedes cardiac differentiation to initiate the first heartbeat

About this item

Full title

Calcium handling precedes cardiac differentiation to initiate the first heartbeat

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2016-10, Vol.5

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The mammalian heartbeat is thought to begin just prior to the linear heart tube stage of development. How the initial contractions are established and the downstream consequences of the earliest contractile function on cardiac differentiation and morphogenesis have not been described. Using high-resolution live imaging of mouse embryos, we observed...

Alternative Titles

Full title

Calcium handling precedes cardiac differentiation to initiate the first heartbeat

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7b0318b9436e4a8fb4d03847c3efd7d4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b0318b9436e4a8fb4d03847c3efd7d4

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.17113

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