Amino-acid site variability among natural and designed proteins
Amino-acid site variability among natural and designed proteins
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Publisher
United States: PeerJ. Ltd
Journal title
Language
English
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Publisher
United States: PeerJ. Ltd
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Scope and Contents
Contents
Computational protein design attempts to create protein sequences that fold stably into pre-specified structures. Here we compare alignments of designed proteins to alignments of natural proteins and assess how closely designed sequences recapitulate patterns of sequence variation found in natural protein sequences. We design proteins using Rosetta...
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Full title
Amino-acid site variability among natural and designed proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_7b16924589a542e7a96736ca4fbd8f7b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b16924589a542e7a96736ca4fbd8f7b
Other Identifiers
ISSN
2167-8359
E-ISSN
2167-8359
DOI
10.7717/peerj.211
