Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculos...
Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Variability in bacterial sterilization is a key feature of
Mycobacterium tuberculosis
(Mtb) disease. In a population of human macrophages, there are macrophages that restrict Mtb growth and those that do not. However, the sources of heterogeneity in macrophage state during Mtb infection are poorly understood. Here, we perform RNAseq on restri...
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Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
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TN_cdi_doaj_primary_oai_doaj_org_article_7b1cd08cca8c4de48969bd62ffdea2d7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b1cd08cca8c4de48969bd62ffdea2d7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10065-8