RAGE-TXNIP axis drives inflammation in Alzheimer’s by targeting Aβ to mitochondria in microglia
RAGE-TXNIP axis drives inflammation in Alzheimer’s by targeting Aβ to mitochondria in microglia
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Alzheimer’s disease (AD) is the most common form of dementia characterized by progressive memory loss and cognitive decline. Although neuroinflammation and oxidative stress are well-recognized features of AD, their correlations with the early molecular events characterizing the pathology are not yet well clarified. Here, we characterize the role of...
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RAGE-TXNIP axis drives inflammation in Alzheimer’s by targeting Aβ to mitochondria in microglia
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TN_cdi_doaj_primary_oai_doaj_org_article_7b3ca2b0658145d882f977f11b798abb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b3ca2b0658145d882f977f11b798abb
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-04758-0
