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Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recogn...

Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recogn...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b673fb3eadc42758b70697559eced47

Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recognition

About this item

Full title

Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recognition

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2025-07, Vol.21 (7), p.e1013300

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Human herpesvirus 6B (HHV-6B), a β-herpesvirus that significantly threatens immunocompromised individuals, currently lacks targeted antiviral therapies or vaccines. Glycoprotein B (gB), the primary mediator of membrane fusion during viral entry, is a key target for neutralizing antibody (nAb) and vaccine development. In this study, we determined a...

Alternative Titles

Full title

Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recognition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7b673fb3eadc42758b70697559eced47

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b673fb3eadc42758b70697559eced47

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1013300

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