Radiation induces long‐term muscle fibrosis and promotes a fibrotic phenotype in fibro‐adipogenic pr...
Radiation induces long‐term muscle fibrosis and promotes a fibrotic phenotype in fibro‐adipogenic progenitors
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Heidelberg: John Wiley & Sons, Inc
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Language
English
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Publisher
Heidelberg: John Wiley & Sons, Inc
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BackgroundRadiation-induced muscle pathology, characterized by muscle atrophy and fibrotic tissue accumulation, is the most common debilitating late effect of therapeutic radiation exposure particularly in juvenile cancer survivors. In healthy muscle, fibro/adipogenic progenitors (FAPs) are required for muscle maintenance and regeneration, while in...
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Radiation induces long‐term muscle fibrosis and promotes a fibrotic phenotype in fibro‐adipogenic progenitors
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TN_cdi_doaj_primary_oai_doaj_org_article_7b76464a461644d6baba5850004e0251
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b76464a461644d6baba5850004e0251
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ISSN
2190-5991
E-ISSN
2190-6009
DOI
10.1002/jcsm.13320
