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Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b9677d83e734c9bb4414abb7d975e62

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

About this item

Full title

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

Publisher

London: Nature Publishing Group UK

Journal title

Molecular systems biology, 2020-12, Vol.16 (12), p.e9819-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Alzheimer’s disease (AD) is characterized by the appearance of amyloid‐β plaques, neurofibrillary tangles, and inflammation in brain regions involved in memory. Using mass spectrometry, we have quantified the phosphoproteome of the CK‐p25, 5XFAD, and Tau P301S mouse models of neurodegeneration. We identified a shared response involving Siglec‐F whi...

Alternative Titles

Full title

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7b9677d83e734c9bb4414abb7d975e62

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b9677d83e734c9bb4414abb7d975e62

Other Identifiers

ISSN

1744-4292

E-ISSN

1744-4292

DOI

10.15252/msb.20209819

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