A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas
A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas
About this item
Full title
Author / Creator
Dahia, Patricia L M , Ross, Ken N , Wright, Matthew E , Hayashida, César Y , Santagata, Sandro , Barontini, Marta , Kung, Andrew L , Sanso, Gabriela , Powers, James F , Tischler, Arthur S , Hodin, Richard , Heitritter, Shannon , Moore, Francis , Dluhy, Robert , Sosa, Julie Ann , Ocal, I Tolgay , Benn, Diana E , Marsh, Deborah J , Robinson, Bruce G , Schneider, Katherine , Garber, Judy , Arum, Seth M , Korbonits, Márta , Grossman, Ashley , Pigny, Pascal , Toledo, Sérgio P A , Nosé, Vania , Li, Cheng and Stiles, Charles D
Publisher
United States: Public Library of Science (PLoS)
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science (PLoS)
More information
Scope and Contents
Contents
Pheochromocytomas are neural crest-derived tumors that arise from inherited or sporadic mutations in at least six independent genes. The proteins encoded by these multiple genes regulate distinct functions. We show here a functional link between tumors with VHL mutations and those with disruption of the genes encoding for succinate dehydrogenase (S...
Alternative Titles
Full title
A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas
Authors, Artists and Contributors
Author / Creator
Ross, Ken N
Wright, Matthew E
Hayashida, César Y
Santagata, Sandro
Barontini, Marta
Kung, Andrew L
Sanso, Gabriela
Powers, James F
Tischler, Arthur S
Hodin, Richard
Heitritter, Shannon
Moore, Francis
Dluhy, Robert
Sosa, Julie Ann
Ocal, I Tolgay
Benn, Diana E
Marsh, Deborah J
Robinson, Bruce G
Schneider, Katherine
Garber, Judy
Arum, Seth M
Korbonits, Márta
Grossman, Ashley
Pigny, Pascal
Toledo, Sérgio P A
Nosé, Vania
Li, Cheng
Stiles, Charles D
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7bb7eecfd11145148cad35a3854632b4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7bb7eecfd11145148cad35a3854632b4
Other Identifiers
ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.0010008