Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity
Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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The human induced pluripotent stem cells (hiPSCs) can generate all the cells composing the human body, theoretically. Therefore, hiPSCs are thought to be a candidate source of stem cells for regenerative medicine. The major challenge of allogeneic hiPSC-derived cell products is their immunogenicity. The hypoimmunogenic cell strategy is allogenic ce...
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Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity
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TN_cdi_doaj_primary_oai_doaj_org_article_7bbef4cf76ae4912aa5b253dcb819c08
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7bbef4cf76ae4912aa5b253dcb819c08
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-024-03810-4
