Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse mo...
Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome
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England: eLife Sciences Publication
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Language
English
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England: eLife Sciences Publication
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Contents
Down syndrome (DS) results in various degrees of cognitive deficits. In DS mouse models, recovery of behavioral and neurophysiological deficits using GABA
R antagonists led to hypothesize an excessive activity of inhibitory circuits in this condition. Nonetheless, whether over-inhibition is present in DS and whether this is due to specific alter...
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Full title
Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_7c0196ad91794721a9c0704d61da30ff
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c0196ad91794721a9c0704d61da30ff
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.58731
