Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Usher syndrome type 1 F (USH1F), caused by mutations in the protocadherin-15 gene (
PCDH15
), is characterized by congenital deafness, lack of balance, and progressive blindness. In hair cells, the receptor cells of the inner ear, PCDH15 is a component of tip links, fine filaments which pull open mechanosensory transduction channels. A simple...
Alternative Titles
Full title
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7c07a295a0974ee8b332825242a40ad2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c07a295a0974ee8b332825242a40ad2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38038-y
