Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorect...
Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorectal Cancer Patient Receiving Binimetinib, Hydroxychloroquine, and Bevacizumab
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Basel, Switzerland: S. Karger AG
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English
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Basel, Switzerland: S. Karger AG
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Activating RAS mutations occur in more than a half of colorectal cancers (CRCs). RAS-mutated CRCs are notoriously difficult to treat given that they are characterized by the aggressive disease course and the lack of appropriate targeted therapies. Recent preclinical studies demonstrated that RAS-mutated cells escape from therapeutic MEK inhibition...
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Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorectal Cancer Patient Receiving Binimetinib, Hydroxychloroquine, and Bevacizumab
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TN_cdi_doaj_primary_oai_doaj_org_article_7c1eed8c564649b0b17db2a565354f31
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c1eed8c564649b0b17db2a565354f31
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ISSN
1662-6575
E-ISSN
1662-6575
DOI
10.1159/000509241