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Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorect...

Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorect...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c1eed8c564649b0b17db2a565354f31

Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorectal Cancer Patient Receiving Binimetinib, Hydroxychloroquine, and Bevacizumab

About this item

Full title

Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorectal Cancer Patient Receiving Binimetinib, Hydroxychloroquine, and Bevacizumab

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Case Reports in Oncology, 2020-08, Vol.13 (2), p.985-989

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Activating RAS mutations occur in more than a half of colorectal cancers (CRCs). RAS-mutated CRCs are notoriously difficult to treat given that they are characterized by the aggressive disease course and the lack of appropriate targeted therapies. Recent preclinical studies demonstrated that RAS-mutated cells escape from therapeutic MEK inhibition...

Alternative Titles

Full title

Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorectal Cancer Patient Receiving Binimetinib, Hydroxychloroquine, and Bevacizumab

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7c1eed8c564649b0b17db2a565354f31

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c1eed8c564649b0b17db2a565354f31

Other Identifiers

ISSN

1662-6575

E-ISSN

1662-6575

DOI

10.1159/000509241

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