Cooperative insulation of regulatory domains by CTCF-dependent physical insulation and promoter comp...
Cooperative insulation of regulatory domains by CTCF-dependent physical insulation and promoter competition
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The specificity of gene expression during development requires the insulation of regulatory domains to avoid inappropriate enhancer-gene interactions. In vertebrates, this insulator function is mostly attributed to clusters of CTCF sites located at topologically associating domain (TAD) boundaries. However, TAD boundaries allow some physical crosst...
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Full title
Cooperative insulation of regulatory domains by CTCF-dependent physical insulation and promoter competition
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TN_cdi_doaj_primary_oai_doaj_org_article_7c35716ba98249bc94a35aa49faec8e9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c35716ba98249bc94a35aa49faec8e9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51602-4
