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Inflammation drives pathogenesis of early intestinal failure-associated liver disease

Inflammation drives pathogenesis of early intestinal failure-associated liver disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c52d7e75d6c46f283bc9179c59ef240

Inflammation drives pathogenesis of early intestinal failure-associated liver disease

About this item

Full title

Inflammation drives pathogenesis of early intestinal failure-associated liver disease

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-02, Vol.14 (1), p.4240-14, Article 4240

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Patients with intestinal failure who receive long-term parenteral nutrition (PN) often develop intestinal failure-associated liver disease (IFALD). Although there are identified risk factors, the early pathogenesis is poorly understood and treatment options are limited. Here, we perform a transcriptomic analysis of liver tissue in a large animal IF...

Alternative Titles

Full title

Inflammation drives pathogenesis of early intestinal failure-associated liver disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7c52d7e75d6c46f283bc9179c59ef240

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c52d7e75d6c46f283bc9179c59ef240

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-54675-9

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