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The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c6bada9dc8c434fa191c36a4398ea29

The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

About this item

Full title

The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-07, Vol.11 (1), p.1-14, Article 3571

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pathogenic bacteria of the genus
Bartonella
can induce vasoproliferative lesions during infection. The underlying mechanisms are unclear, but involve secretion of an unidentified mitogenic factor. Here, we use functional transposon-mutant screening in
Bartonella henselae
to identify such factor as a pro-angiogenic autotransporter, calle...

Alternative Titles

Full title

The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7c6bada9dc8c434fa191c36a4398ea29

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c6bada9dc8c434fa191c36a4398ea29

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-17391-2

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