The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Pathogenic bacteria of the genus
Bartonella
can induce vasoproliferative lesions during infection. The underlying mechanisms are unclear, but involve secretion of an unidentified mitogenic factor. Here, we use functional transposon-mutant screening in
Bartonella henselae
to identify such factor as a pro-angiogenic autotransporter, calle...
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Full title
The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_7c6bada9dc8c434fa191c36a4398ea29
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c6bada9dc8c434fa191c36a4398ea29
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17391-2