De novo active sites for resurrected Precambrian enzymes
De novo active sites for resurrected Precambrian enzymes
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Protein engineering studies often suggest the emergence of completely new enzyme functionalities to be highly improbable. However, enzymes likely catalysed many different reactions already in the last universal common ancestor. Mechanisms for the emergence of completely new active sites must therefore either plausibly exist or at least have existed...
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Full title
De novo active sites for resurrected Precambrian enzymes
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TN_cdi_doaj_primary_oai_doaj_org_article_7c76aaa815614d3a948e230f4b0670e6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c76aaa815614d3a948e230f4b0670e6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms16113
