A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning...
A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2
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Author / Creator
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States) , Losa, Marta , Barozzi, Iros , Osterwalder, Marco , Hermosilla-Aguayo, Viviana , Morabito, Angela , Chacón, Brandon H. , Zarrineh, Peyman , Girdziusaite, Ausra , Benazet, Jean Denis , Zhu, Jianjian , Mackem, Susan , Capellini, Terence D. , Dickel, Diane , Bobola, Nicoletta , Zuniga, Aimée , Visel, Axel , Zeller, Rolf and Selleri, Licia
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
A lingering question in developmental biology has centered on how transcription factors with widespread distribution in vertebrate embryos can perform tissue-specific functions. Here, using the murine hindlimb as a model, we investigate the elusive mechanisms whereby PBX TALE homeoproteins, viewed primarily as HOX cofactors, attain context-specific...
Alternative Titles
Full title
A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2
Authors, Artists and Contributors
Author / Creator
Losa, Marta
Barozzi, Iros
Osterwalder, Marco
Hermosilla-Aguayo, Viviana
Morabito, Angela
Chacón, Brandon H.
Zarrineh, Peyman
Girdziusaite, Ausra
Benazet, Jean Denis
Zhu, Jianjian
Mackem, Susan
Capellini, Terence D.
Dickel, Diane
Bobola, Nicoletta
Zuniga, Aimée
Visel, Axel
Zeller, Rolf
Selleri, Licia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7c9a9b83afdc4ea8afaf6d100fd069b1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c9a9b83afdc4ea8afaf6d100fd069b1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39443-z
