Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori–induced inflamma...
Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori–induced inflammation–driven gastric carcinogenesis
About this item
Full title
Author / Creator
Noto, Jennifer M. , Piazuelo, M. Blanca , Shah, Shailja C. , Romero-Gallo, Judith , Hart, Jessica L. , Di, Chao , Carmichael, James D. , Delgado, Alberto G. , Halvorson, Alese E. , Greevy, Robert A. , Wroblewski, Lydia E. , Sharma, Ayushi , Newton, Annabelle B. , Allaman, Margaret M. , Wilson, Keith T. , Washington, M. Kay , Calcutt, M. Wade , Schey, Kevin L. , Cummings, Bethany P. , Flynn, Charles R. , Zackular, Joseph P. and Peek, Richard M.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Gastric carcinogenesis is mediated by complex interactions among Helicobacter pylori, host, and environmental factors. Here, we demonstrate that H. pylori augmented gastric injury in INS-GAS mice under iron-deficient conditions. Mechanistically, these phenotypes were not driven by alterations in the gastric microbiota; however, discovery-based and...
Alternative Titles
Full title
Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori–induced inflammation–driven gastric carcinogenesis
Authors, Artists and Contributors
Author / Creator
Piazuelo, M. Blanca
Shah, Shailja C.
Romero-Gallo, Judith
Hart, Jessica L.
Di, Chao
Carmichael, James D.
Delgado, Alberto G.
Halvorson, Alese E.
Greevy, Robert A.
Wroblewski, Lydia E.
Sharma, Ayushi
Newton, Annabelle B.
Allaman, Margaret M.
Wilson, Keith T.
Washington, M. Kay
Calcutt, M. Wade
Schey, Kevin L.
Cummings, Bethany P.
Flynn, Charles R.
Zackular, Joseph P.
Peek, Richard M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7d198f5f9fa7400583ab84388b9c0680
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d198f5f9fa7400583ab84388b9c0680
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI147822
