ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expre...
ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Expression of human Apolipoprotein E (APOE) modulates the inflammatory response in an isoform specific manner, with APOE4 isoform eliciting a stronger pro-inflammatory response, suggesting a possible mechanism for worse outcome following traumatic brain injury (TBI). APOE lipidation and stability is modulated by ATP-binding cassette transporter A1...
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ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms
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TN_cdi_doaj_primary_oai_doaj_org_article_7d29a78239c345059d3358e6c078f980
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d29a78239c345059d3358e6c078f980
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-018-0569-2
