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Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflam...

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflam...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d3441596abf4db39ec0dbd7c8ea23d7

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

About this item

Full title

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-11, Vol.15 (1), p.9871-16, Article 9871

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Natural killer (NK) cell function is regulated by a balance of activating and inhibitory signals. Tumor necrosis factor (TNF) is an inflammatory cytokine ubiquitous across homeostasis and disease, yet its role in regulation of NK cells remains unclear. Here, we find upregulation of the immune checkpoint protein, T cell immunoglobulin and mucin doma...

Alternative Titles

Full title

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7d3441596abf4db39ec0dbd7c8ea23d7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d3441596abf4db39ec0dbd7c8ea23d7

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-54232-y

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