Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory...
Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory consequences of ERV expression
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England: BMJ Publishing Group LTD
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English
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England: BMJ Publishing Group LTD
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BackgroundEndogenous retroviruses (ERVs) play a role in a variety of biological processes, including embryogenesis and cancer. DNA methyltransferase inhibitors (DNMTi)-induced ERV expression triggers interferon responses in ovarian cancer cells via the viral sensing machinery. Baseline expression of ERVs also occurs in cancer cells, though this pro...
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Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory consequences of ERV expression
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TN_cdi_doaj_primary_oai_doaj_org_article_7d3baf3de1394dd9863a83a84f696bd1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d3baf3de1394dd9863a83a84f696bd1
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001519
