Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex...
Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Thiosemicarbazones (TSC) and their metal complexes display diverse biological activities and are active against multiple pathological conditions ranging from microbial infections to abnormal cell proliferation. Ribonucleotide reductase (RNR) is considered one of the main targets of TSCs, yet, the existence of additional targets, differently respons...
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Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study
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TN_cdi_doaj_primary_oai_doaj_org_article_7d61f468503745d19cb2217ef5f0efa8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d61f468503745d19cb2217ef5f0efa8
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2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-67439-y
