Rational design, synthesis, in vitro, and in-silico studies of pyrazole‑phthalazine hybrids as new α...
Rational design, synthesis, in vitro, and in-silico studies of pyrazole‑phthalazine hybrids as new α‑glucosidase inhibitors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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This paper describes the design, development, synthesis, in silico, and in vitro evaluation of fourteen novel heterocycle hybrids as inhibitors of the α-glucosidase enzyme. The primary aim of this study was to explore the potential of novel pyrazole-phthalazine hybrids as selective inhibitors of α-glucosidase, an enzyme involved in carbohydrate met...
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Rational design, synthesis, in vitro, and in-silico studies of pyrazole‑phthalazine hybrids as new α‑glucosidase inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_7d6e407c936043c884972cd5d1b8c332
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d6e407c936043c884972cd5d1b8c332
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-87258-3
