Herpes Simplex Virus Type 2 Blocks IFN-β Production through the Viral UL24 N-Terminal Domain-Mediate...
Herpes Simplex Virus Type 2 Blocks IFN-β Production through the Viral UL24 N-Terminal Domain-Mediated Inhibition of IRF-3 Phosphorylation
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Full title
Author / Creator
Zhang, Binman , Li, Yuncheng , Yang, Ping , He, Siyu , Li, Weilin , Li, Miaomiao , Hu, Qinxue and Zhang, Mudan
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Herpes simplex virus type 2 (HSV-2) is a sexually transmitted virus, the cause of genital herpes, and its infection can increase the risk of HIV-1 infection. After initial infection, HSV-2 can establish lifelong latency within the nervous system, which is likely associated with the virus-mediated immune evasion. In this study, we found that HSV-2 U...
Alternative Titles
Full title
Herpes Simplex Virus Type 2 Blocks IFN-β Production through the Viral UL24 N-Terminal Domain-Mediated Inhibition of IRF-3 Phosphorylation
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7d94ffa6440241e6b4d0dc9e599f44cc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d94ffa6440241e6b4d0dc9e599f44cc
Other Identifiers
ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v16101601
