Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate ol...
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages
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Author / Creator
Fang, Weishan , Bi, Decheng , Zheng, Ruijin , Cai, Nan , Xu, Hong , Zhou, Rui , Lu, Jun , Wan, Min and Xu, Xu
Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Alginate, a natural acidic polysaccharide extracted from marine brown seaweeds, is composed of different blocks of β-(1, 4)-D-mannuronate (M) and its C-5 epimer α-(1, 4)-L-guluronate (G). Alginate-derived guluronate oligosaccharide (GOS) readily activates macrophages. However, to understand its role in immune responses, further studies are needed t...
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Full title
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages
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TN_cdi_doaj_primary_oai_doaj_org_article_7d965d16a035441bab4e51b87eefd8ae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d965d16a035441bab4e51b87eefd8ae
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-01868-0
