A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapit...
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses
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Publisher
England: The Company of Biologists Ltd
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Language
English
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England: The Company of Biologists Ltd
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Contents
Although β-blockers can be used to eliminate stress-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT), this treatment is unsuccessful in ∼25% of cases. Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) generated from these patients have potential for use in investigating the...
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Full title
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses
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TN_cdi_doaj_primary_oai_doaj_org_article_7de97dc48ab74877a0bff6bbe23063ab
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7de97dc48ab74877a0bff6bbe23063ab
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.026823
