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A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease

A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e19e8df597247648f62daff3c3765f3

A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease

About this item

Full title

A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2022-01, Vol.11

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Insulin resistance (IR) contributes to the pathophysiology of diabetes, dementia, viral infection, and cardiovascular disease. Drug repurposing (DR) may identify treatments for IR; however, barriers include uncertainty whether in vitro transcriptomic assays yield quantitative pharmacological data, or how to optimise assay design to best reflect in...

Alternative Titles

Full title

A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7e19e8df597247648f62daff3c3765f3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e19e8df597247648f62daff3c3765f3

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.68832

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