A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease
A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Insulin resistance (IR) contributes to the pathophysiology of diabetes, dementia, viral infection, and cardiovascular disease. Drug repurposing (DR) may identify treatments for IR; however, barriers include uncertainty whether in vitro transcriptomic assays yield quantitative pharmacological data, or how to optimise assay design to best reflect in...
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A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease
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TN_cdi_doaj_primary_oai_doaj_org_article_7e19e8df597247648f62daff3c3765f3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e19e8df597247648f62daff3c3765f3
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.68832