The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of...
The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer
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Author / Creator
Xu, Youqin , Song, Mu , Hong, Ziyang , Chen, Wancheng , Zhang, Qianbing , Zhou, Jianlong , Yang, Chao , He, Zilong , Yu, Juanjuan , Peng, Xiaolin , Zhu, Qiuhong , Li, Shaotian , Ji, Kaiyuan , Liu, Minfeng and Zuo, Qiang
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Posttranscriptional modification of tumor-associated factors plays a pivotal role in breast cancer progression. However, the underlying mechanism remains unknown. M6A modifications in cancer cells are dynamic and reversible and have been found to impact tumor initiation and progression through various mechanisms. In this study, we explored the regu...
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Full title
The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7e27476d739d4b4e8da5e5b159a3fa05
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e27476d739d4b4e8da5e5b159a3fa05
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02581-1
