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Engineered Synthetic STxB for Enhanced Cytosolic Delivery

Engineered Synthetic STxB for Enhanced Cytosolic Delivery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e3ce7fe20a4467496df4c2ec0b3aca2

Engineered Synthetic STxB for Enhanced Cytosolic Delivery

About this item

Full title

Engineered Synthetic STxB for Enhanced Cytosolic Delivery

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2023-04, Vol.12 (9), p.1291

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Many molecular targets for cancer therapy are located in the cytosol. Therapeutic macromolecules are generally not able to spontaneously translocate across membranes to reach these cytosolic targets. Therefore a strong need exists for tools that enhance cytosolic delivery. Shiga toxin B-subunit (STxB) is used to deliver therapeutic principles to di...

Alternative Titles

Full title

Engineered Synthetic STxB for Enhanced Cytosolic Delivery

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7e3ce7fe20a4467496df4c2ec0b3aca2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e3ce7fe20a4467496df4c2ec0b3aca2

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells12091291

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