Ryanodine Receptor Mediated Calcium Release Contributes to Ferroptosis Induced in Primary Hippocampa...
Ryanodine Receptor Mediated Calcium Release Contributes to Ferroptosis Induced in Primary Hippocampal Neurons by GPX4 Inhibition
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Ferroptosis, a newly described form of regulated cell death, is characterized by the iron-dependent accumulation of lipid peroxides, glutathione depletion, mitochondrial alterations, and enhanced lipoxygenase activity. Inhibition of glutathione peroxidase 4 (GPX4), a key intracellular antioxidant regulator, promotes ferroptosis in different cell ty...
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Full title
Ryanodine Receptor Mediated Calcium Release Contributes to Ferroptosis Induced in Primary Hippocampal Neurons by GPX4 Inhibition
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TN_cdi_doaj_primary_oai_doaj_org_article_7e44a1aca8de4abd84363887a9a07e2c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e44a1aca8de4abd84363887a9a07e2c
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ISSN
2076-3921
E-ISSN
2076-3921
DOI
10.3390/antiox12030705
