MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage...
MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Despite improvements in overall survival, only a modest percentage of patients survives high-risk medulloblastoma. The devastating side effects of radiation and chemotherapy substantially reduce quality of life for surviving patients. Here, using genomic screens, we identified
miR-584-5p
as a potent therapeutic adjuvant that potentiates medul...
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Full title
MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_7e6b817f247d44dd9e1ce5001fd43f4d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e6b817f247d44dd9e1ce5001fd43f4d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06808-8
