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Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e8570c907ad436eb02c29b0dbf990be

Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

About this item

Full title

Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

The Journal of Pathology: Clinical Research, 2021-11, Vol.7 (6), p.565-576

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The majority of supratentorial ependymomas in children contain oncogenic fusions, such as ZFTA–RELA or YAP1‐MAMLD1. In contrast, posterior fossa (PF) ependymomas lack recurrent somatic mutations and are classified based on gene expression or methylation profiling into group A (PFA) and group B (PFB). We have applied a novel method, NanoString nCoun...

Alternative Titles

Full title

Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7e8570c907ad436eb02c29b0dbf990be

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e8570c907ad436eb02c29b0dbf990be

Other Identifiers

ISSN

2056-4538

E-ISSN

2056-4538

DOI

10.1002/cjp2.236

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