Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome
Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome
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Author / Creator
Dalene Skarping, Karin , Arning, Larissa , Petersén, Åsa , Nguyen, Huu Phuc , Gebre-Medhin, Samuel , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , Department of Experimental Medical Science , Division of Clinical Genetics , Department of Laboratory Medicine , Avdelningen för klinisk genetik , Institutionen för kliniska vetenskaper, Lund , Strategic research areas (SRA) , Lunds universitet , Translational Neuroendocrinology , Department of Clinical Sciences, Lund , Profilområden och andra starka forskningsmiljöer , Sektion IV , Lund University , Section IV , Psychiatry (Lund) , Institutionen för laboratoriemedicin , Psykiatri, Lund , Institutionen för experimentell medicinsk vetenskap , Profile areas and other strong research environments , Translationell neuroendokrinologi and MultiPark: Multidisciplinary research focused on Parkinson's disease
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
DNA mismatch repair (MMR) is thought to contribute to the onset and progression of Huntington disease (HD) by promoting somatic expansion of the pathogenic CAG nucleotide repeat in the huntingtin gene (
HTT
). Here we have studied constitutional
HTT
CAG repeat size in two cohorts of individuals with Lynch syndrome (LS) carrying heterozy...
Alternative Titles
Full title
Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome
Authors, Artists and Contributors
Author / Creator
Arning, Larissa
Petersén, Åsa
Nguyen, Huu Phuc
Gebre-Medhin, Samuel
Faculty of Medicine
Medicinska fakulteten
Strategiska forskningsområden (SFO)
Department of Experimental Medical Science
Division of Clinical Genetics
Department of Laboratory Medicine
Avdelningen för klinisk genetik
Institutionen för kliniska vetenskaper, Lund
Strategic research areas (SRA)
Lunds universitet
Translational Neuroendocrinology
Department of Clinical Sciences, Lund
Profilområden och andra starka forskningsmiljöer
Sektion IV
Lund University
Section IV
Psychiatry (Lund)
Institutionen för laboratoriemedicin
Psykiatri, Lund
Institutionen för experimentell medicinsk vetenskap
Profile areas and other strong research environments
Translationell neuroendokrinologi
MultiPark: Multidisciplinary research focused on Parkinson's disease
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7e8f2306aea34783a1ca07f753e296b9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e8f2306aea34783a1ca07f753e296b9
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-54277-5
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