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Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in in...

Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e9d891138304446a4c48cacf658a1c5

Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

About this item

Full title

Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

Publisher

London: Nature Publishing Group UK

Journal title

Translational psychiatry, 2022-09, Vol.12 (1), p.404-404, Article 404

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Interleukin-18 (IL18) is an inflammatory cytokine that is related to psychiatric disorders such as depression and cognitive impairment. We previously found that IL18 deficiency may cause hippocampal impairment, resulting in depression-like behavioral changes. However, the potential role of IL18 in stressful conditions remains uncertain. In the pres...

Alternative Titles

Full title

Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7e9d891138304446a4c48cacf658a1c5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e9d891138304446a4c48cacf658a1c5

Other Identifiers

ISSN

2158-3188

E-ISSN

2158-3188

DOI

10.1038/s41398-022-02175-7

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