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A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous canc...

A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous canc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7ea57068e99f4b3d9f9d8844f0926591

A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs

About this item

Full title

A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-10, Vol.10 (1), p.18311-18311, Article 18311

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inhibition of programmed death 1 (PD-1), expressed on activated T cells, can break through immune resistance and elicit durable responses in human melanoma as well as other types of cancers. Canine oral malignant melanoma is one of the most aggressive tumors bearing poor prognosis due to its high metastatic potency. However, there are few effective...

Alternative Titles

Full title

A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7ea57068e99f4b3d9f9d8844f0926591

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7ea57068e99f4b3d9f9d8844f0926591

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-75533-4

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