Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and E...
Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy
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Author / Creator
Hameed P, Shahul , Bharatham, Nagakumar , Katagihallimath, Nainesh , Sharma, Sreevalli , Nandishaiah, Radha , Shanbhag, Anirudh P. , Thomas, Teby , Narjari, Riya , Sarma, Maitrayee , Bhowmik, Purnendu , Amar, Prakruthi , Ravishankar, Rajani , Jayaraman, Ramesh , Muthan, Kubendran , Subbiah, Ramesh , Ramachandran, Vasanthi , Balasubramanian, V. and Datta, Santanu
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The mechanism of efflux is a tour-de-force in the bacterial armoury that has thwarted the development of novel antibiotics. We report the discovery of a novel chemical series with potent antibacterial properties that was engineered to overcome efflux liability. Compounds liable to efflux specifically via the Resistance Nodulation and cell Division...
Alternative Titles
Full title
Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy
Authors, Artists and Contributors
Author / Creator
Bharatham, Nagakumar
Katagihallimath, Nainesh
Sharma, Sreevalli
Nandishaiah, Radha
Shanbhag, Anirudh P.
Thomas, Teby
Narjari, Riya
Sarma, Maitrayee
Bhowmik, Purnendu
Amar, Prakruthi
Ravishankar, Rajani
Jayaraman, Ramesh
Muthan, Kubendran
Subbiah, Ramesh
Ramachandran, Vasanthi
Balasubramanian, V.
Datta, Santanu
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7ea9439734d44af0a1b4d9b9699003a2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7ea9439734d44af0a1b4d9b9699003a2
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-25407-7