Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemi...
Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice
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Author / Creator
Isidro-Hernández, Marta , Casado-García, Ana , Oak, Ninad , Alemán-Arteaga, Silvia , Ruiz-Corzo, Belén , Martínez-Cano, Jorge , Mayado, Andrea , Sánchez, Elena G. , Blanco, Oscar , Gaspar, Ma Luisa , Orfao, Alberto , Alonso-López, Diego , De Las Rivas, Javier , Riesco, Susana , Prieto-Matos, Pablo , González-Murillo, África , Criado, Francisco Javier García , Cenador, María Begoña García , Ramírez-Orellana, Manuel , de Andrés, Belén , Vicente-Dueñas, Carolina , Cobaleda, César , Nichols, Kim E. and Sánchez-García, Isidro
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The initial steps of B-cell acute lymphoblastic leukemia (B-ALL) development usually pass unnoticed in children. Several preclinical studies have shown that exposure to immune stressors triggers the transformation of preleukemic B cells to full-blown B-ALL, but how this takes place is still a longstanding and unsolved challenge. Here we show that d...
Alternative Titles
Full title
Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice
Authors, Artists and Contributors
Author / Creator
Casado-García, Ana
Oak, Ninad
Alemán-Arteaga, Silvia
Ruiz-Corzo, Belén
Martínez-Cano, Jorge
Mayado, Andrea
Sánchez, Elena G.
Blanco, Oscar
Gaspar, Ma Luisa
Orfao, Alberto
Alonso-López, Diego
De Las Rivas, Javier
Riesco, Susana
Prieto-Matos, Pablo
González-Murillo, África
Criado, Francisco Javier García
Cenador, María Begoña García
Ramírez-Orellana, Manuel
de Andrés, Belén
Vicente-Dueñas, Carolina
Cobaleda, César
Nichols, Kim E.
Sánchez-García, Isidro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7edbe4149620489b8ca43749dc557848
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7edbe4149620489b8ca43749dc557848
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-40961-z
