Chlorpromazine affects glioblastoma bioenergetics by interfering with pyruvate kinase M2
Chlorpromazine affects glioblastoma bioenergetics by interfering with pyruvate kinase M2
About this item
Full title
Author / Creator
Abbruzzese, Claudia , Matteoni, Silvia , Matarrese, Paola , Signore, Michele , Ascione, Barbara , Iessi, Elisabetta , Gurtner, Aymone , Sacconi, Andrea , Ricci-Vitiani, Lucia , Pallini, Roberto , Pace, Andrea , Villani, Veronica , Polo, Andrea , Costantini, Susan , Budillon, Alfredo , Ciliberto, Gennaro and Paggi, Marco G.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Glioblastoma (GBM) is the most frequent and lethal brain tumor, whose therapeutic outcome - only partially effective with current schemes - places this disease among the unmet medical needs, and effective therapeutic approaches are urgently required. In our attempts to identify repositionable drugs in glioblastoma therapy, we identified the neurole...
Alternative Titles
Full title
Chlorpromazine affects glioblastoma bioenergetics by interfering with pyruvate kinase M2
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7ee581ac984649568940e3ed50b36ec0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7ee581ac984649568940e3ed50b36ec0
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-06353-3
