Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against Ga...
Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity
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Author / Creator
Regmi, Shobha , Pathak, Shiva , Thanh, Tung Pham , Nguyen, Tiep Tien , Sung, Jong-Hyuk , Yook, Simmyung , Kim, Jong Oh , Yong, Chul Soon , Choi, Inho , Doh, Kyoung-Oh , Park, Pil-Hoon , Park, Jun-Beom , Seo, Yoojin , Kim, Bieong-Kil , Lee, Dong-Mok , Moon, Ik-Jae , Kim, Hyung-Sik and Jeong, Jee-Heon
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Systemic inflammatory response syndrome (SIRS) is common in severe fulminant hepatic failure (FHF) and has a high mortality rate (20-50%) due to irreversible cerebral edema or sepsis. Stem cell-based treatment has emerged as a promising alternative therapeutic strategy to prolong the survival of patients suffering from FHF via the inhibition of SIR...
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Full title
Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity
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TN_cdi_doaj_primary_oai_doaj_org_article_7f2d9c25befd4154adca588c99ed3e06
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f2d9c25befd4154adca588c99ed3e06
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-019-1337-3