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Toll-like receptor 4 (TLR4): new insight immune and aging

Toll-like receptor 4 (TLR4): new insight immune and aging

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f318e570edd460dbc1c411fd9971cbb

Toll-like receptor 4 (TLR4): new insight immune and aging

About this item

Full title

Toll-like receptor 4 (TLR4): new insight immune and aging

Publisher

London: BioMed Central Ltd

Journal title

Immunity & ageing, 2023-11, Vol.20 (1), p.1-67, Article 67

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

TLR4, a transmembrane receptor, plays a central role in the innate immune response. TLR4 not only engages with exogenous ligands at the cellular membrane’s surface but also interacts with intracellular ligands, initiating intricate intracellular signaling cascades. Through MyD88, an adaptor protein, TLR4 activates transcription factors NF-κB and AP...

Alternative Titles

Full title

Toll-like receptor 4 (TLR4): new insight immune and aging

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7f318e570edd460dbc1c411fd9971cbb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f318e570edd460dbc1c411fd9971cbb

Other Identifiers

ISSN

1742-4933

E-ISSN

1742-4933

DOI

10.1186/s12979-023-00383-3

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