Cancer treatment monitoring using cell-free DNA fragmentomes
Cancer treatment monitoring using cell-free DNA fragmentomes
About this item
Full title
Author / Creator
van ’t Erve, Iris , Alipanahi, Bahar , Lumbard, Keith , Skidmore, Zachary L. , Rinaldi, Lorenzo , Millberg, Laurel K. , Carey, Jacob , Chesnick, Bryan , Cristiano, Stephen , Portwood, Carter , Wu, Tony , Peters, Erica , Bolhuis, Karen , Punt, Cornelis J. A. , Tom, Jennifer , Bach, Peter B. , Dracopoli, Nicholas C. , Meijer, Gerrit A. , Scharpf, Robert B. , Velculescu, Victor E. , Fijneman, Remond J. A. and Leal, Alessandro
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Circulating cell-free DNA (cfDNA) assays for monitoring individuals with cancer typically rely on prior identification of tumor-specific mutations. Here, we develop a tumor-independent and mutation-independent approach (DELFI-tumor fraction, DELFI-TF) using low-coverage whole genome sequencing to determine the cfDNA tumor fraction and validate the...
Alternative Titles
Full title
Cancer treatment monitoring using cell-free DNA fragmentomes
Authors, Artists and Contributors
Author / Creator
Alipanahi, Bahar
Lumbard, Keith
Skidmore, Zachary L.
Rinaldi, Lorenzo
Millberg, Laurel K.
Carey, Jacob
Chesnick, Bryan
Cristiano, Stephen
Portwood, Carter
Wu, Tony
Peters, Erica
Bolhuis, Karen
Punt, Cornelis J. A.
Tom, Jennifer
Bach, Peter B.
Dracopoli, Nicholas C.
Meijer, Gerrit A.
Scharpf, Robert B.
Velculescu, Victor E.
Fijneman, Remond J. A.
Leal, Alessandro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8005c4ee68144cd383ff212f1b67d00a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8005c4ee68144cd383ff212f1b67d00a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-53017-7
