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Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinfla...

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinfla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8050b454059242799298a70205d8078a

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease

About this item

Full title

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease

Publisher

England: BioMed Central Ltd

Journal title

Translational Neurodegeneration, 2022-01, Vol.11 (1), p.2-2, Article 2

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease. It has been proposed that neuroinflammation might be an intervening variable, but the underlying mechanisms are currently unk...

Alternative Titles

Full title

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8050b454059242799298a70205d8078a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8050b454059242799298a70205d8078a

Other Identifiers

ISSN

2047-9158

E-ISSN

2047-9158

DOI

10.1186/s40035-021-00277-8

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