Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision
Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We report the molecular basis of
Aspergillus fumigatus
oryzin, allergen Asp f 13, or alkaline proteinase ALP1, containing the sequence motif His–Asp–Ser of the subtilisin family, structure, and function at atomic detail. Given the resolution of the data (1.06 Å), we use fragment molecular replacement with ideal polyalanine α-helices to determ...
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Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision
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TN_cdi_doaj_primary_oai_doaj_org_article_8053a392335e4a0e96cb0fd4081b0a96
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8053a392335e4a0e96cb0fd4081b0a96
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-45028-z