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Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision

Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8053a392335e4a0e96cb0fd4081b0a96

Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision

About this item

Full title

Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-10, Vol.13 (1), p.17926-17926, Article 17926

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We report the molecular basis of
Aspergillus fumigatus
oryzin, allergen Asp f 13, or alkaline proteinase ALP1, containing the sequence motif His–Asp–Ser of the subtilisin family, structure, and function at atomic detail. Given the resolution of the data (1.06 Å), we use fragment molecular replacement with ideal polyalanine α-helices to determ...

Alternative Titles

Full title

Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8053a392335e4a0e96cb0fd4081b0a96

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8053a392335e4a0e96cb0fd4081b0a96

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-45028-z

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