Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the t...
Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis
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Publisher
New Zealand: Taylor & Francis Ltd
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Language
English
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Publisher
New Zealand: Taylor & Francis Ltd
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Contents
Triptolide (TP) exhibits immunosuppressive, cartilage-protective and anti-inflammatory effects in rheumatoid arthritis. However, the toxicity of TP limits its widespread use. To decrease the toxic effects, we developed a novel nano-drug carrier system containing TP using poly-γ-glutamic acid-grafted di-tert-butyl L-aspartate hydrochloride (PAT). PA...
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Full title
Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis
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TN_cdi_doaj_primary_oai_doaj_org_article_8066ce4c48e948cba3c554cfbda463aa
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8066ce4c48e948cba3c554cfbda463aa
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ISSN
1178-2013,1176-9114
E-ISSN
1178-2013
DOI
10.2147/IJN.S151233