Targeting RNA by small molecules: comparative structural and thermodynamic aspects of aristololactam...
Targeting RNA by small molecules: comparative structural and thermodynamic aspects of aristololactam-β-D-glucoside and daunomycin binding to tRNA(phe)
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United States: Public Library of Science (PLoS)
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English
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United States: Public Library of Science (PLoS)
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Interaction of aristololactam-β-D-glucoside and daunomycin with tRNA(phe) was investigated using various biophysical techniques.
Absorption and fluorescence studies revealed that both the compounds bind tRNA(phe) non-cooperatively. The binding of daunomycin was about one order of magnitude higher than that of aristololactam-β-D-glucoside. Strong...
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Full title
Targeting RNA by small molecules: comparative structural and thermodynamic aspects of aristololactam-β-D-glucoside and daunomycin binding to tRNA(phe)
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TN_cdi_doaj_primary_oai_doaj_org_article_80810db337ac4618b64d65309a00d6fb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_80810db337ac4618b64d65309a00d6fb
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023186
