Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress
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Wang, Jinyang , Wen, Yaxin , Zhao, Wentao , Zhang, Yan , Lin, Furong , Ouyang, Cong , Wang, Huihui , Yao, Lizheng , Ma, Huanhuan , Zhuo, Yue , Huang, Huiying , Shi, Xiulin , Feng, Liubin , Lin, Donghai , Jiang, Bin and Li, Qinxi
Publisher
Cambridge: eLife Science Publications, Ltd
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English
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Cambridge: eLife Science Publications, Ltd
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Accumulating evidence indicates that acetate is increased under energy stress conditions such as those that occur in diabetes mellitus and prolonged starvation. However, how and where acetate is produced and the nature of its biological significance are largely unknown. We observed overproduction of acetate to concentrations comparable to those of...
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Full title
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress
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TN_cdi_doaj_primary_oai_doaj_org_article_809ace1bf8b044489345d52c3839f741
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_809ace1bf8b044489345d52c3839f741
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.87419