Purifying selection of long dsRNA is the first line of defense against false activation of innate im...
Purifying selection of long dsRNA is the first line of defense against false activation of innate immunity
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Mobile elements comprise a large fraction of metazoan genomes. Accumulation of mobile elements is bound to produce multiple putative double-stranded RNA (dsRNA) structures within the transcriptome. These endogenous dsRNA structures resemble viral RNA and may trigger false activation of the innate immune response, leading to severe damage to the hos...
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Purifying selection of long dsRNA is the first line of defense against false activation of innate immunity
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TN_cdi_doaj_primary_oai_doaj_org_article_80a92672d7614a75a5805c2a67aea2a3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_80a92672d7614a75a5805c2a67aea2a3
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-020-1937-3
