Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitof...
Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitofusin 2-deficient cells
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Wang, Yueyang , Troughton, Lee D , Xu, Fan , Chatterjee, Aritra , Ding, Chang , Zhao, Han , Cifuentes, Laura P , Wagner, Ryan B , Wang, Tianqi , Tan, Shelly , Chen, Jingjuan , Li, Linlin , Umulis, David , Kuang, Shihuan , Suter, Daniel M , Yuan, Chongli , Chan, Deva , Huang, Fang , Oakes, Patrick W and Deng, Qing
Publisher
England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Cell spreading and migration play central roles in many physiological and pathophysiological processes. We have previously shown that MFN2 regulates the migration of human neutrophil-like cells via suppressing Rac activation. Here, we show that in mouse embryonic fibroblasts, MFN2 suppresses RhoA activation and supports cell polarization. After ini...
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Full title
Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitofusin 2-deficient cells
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TN_cdi_doaj_primary_oai_doaj_org_article_80d2f4bf1af140f981ecc2ce933a1e23
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_80d2f4bf1af140f981ecc2ce933a1e23
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.88828
